Characterization of a human cell line stably over-expressing the candidate oncogene, dual specificity phosphatase 12.

Analysis of chromosomal rearrangements within primary tumors has been influential in the identification of novel oncogenes.Identification of the "driver" gene(s) within cancer-derived amplicons is, however, hampered by the fact that most amplicons contain many gene products.Amplification of 1q21-1q23 is strongly associated with liposarcomas and mic

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Social Shaping of Technological Trajectories of Shinkansen

The Tokaido Shinkansen began operating in 1964 and ran at globally unprecedented speeds of more than 200 kmph.Comparison with the operating speed of aircraft necessitated further improvement of the operating speed of Shinkansen.Nevertheless, there was no improvement until 20 years.During that period, the maximum speed of test cars, the highest tech

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